Ancient Guardians is a Yu-Gi-Oh! booster pack that was released in May 2021. This expansion introduces three brand-new archetypes: "Ogdoadic," "Ursarctic," and "Solfachord." The "Ogdoadic" archetypes focus on powerful Reptile monsters with graveyard effects, while "Ursarctic" introduces a new Synchro-based mechanic without the need for level adjustments. "Solfachord" offers a new take on Pendulum Summoning with a musical theme.

A display contains 24 booster packs with 7 cards each.

The set contains a total of 60 cards:

40 Rares
15 Super Rares
10 Ultra Rares
Ancient Guardians also offers the chance to find Collector's Rare cards, which are highly collectible and visually striking.

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